CYRIS^® FLOX

Our technology allows researchers to measure changes in cell morphology and metabolism automatically and in a fully controllable atmospheric environment. It improves efficiency and work performance through the continuous observation of multiple data:

dissolved oxygen
cellular oxygen consumption rate (OCR)
pH
extracellular acidification rate (ECAR)
cellular impedance (magnitude and phase) and microscopic imaging

AUTOMATION AND PREDICTABLE RESEARCH RESULTS, IN MUCH LESS TIME

Automated detection of multiple cellular key parameters

Full label-free real-time measurement for days or weeks

Automatic climatisation (temperature, gas atmosphere and humidity) of the measurement environment

Investigation of up to 24 different treatable cell samples or references in parallel

Automatic supply of culture media and addition plus washout of active substances

Automatic disposal of exhausted media, pooled or retraceable to samples (subsequent investigation possible)

USB Ports

ON/OFF Button

Status light

Freely programmable sequences of experiments and output of raw and processed data

Excellent ergonomics thanks to the tilted touchscreen display

Reduced working time standing in front of the device

CELL VIABILITY MEASURED IN

REAL-TIME

CYRIS® FLOX constantly monitors cell metabolism by measuring the OCR and the ECAR, and cell morphology by measuring cellular impedance and microscopic imaging.

Learn more about the performances of CYRIS® FLOX

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INCYTOИ® platforms steadily observe cell viability automatically and in a fully controllable atmospheric environment

HOW IT WORKS

During the measurement, living adherent cells are cultivated and treated in the 24 independent test chambers of a special sensor-equipped microtiter plate (sensor plate), located in a temperature- and atmosphere- controlled climatic chamber.

A fully automated pipetting robot supplies and disposes of media and drugs in all 24 test chambers. This life support fluidic system allows the cells to be monitored and treated in the sensor plate for days up to several weeks in vital conditions and free of disturbance and contamination.

All measurements and treatment protocols in the sensor plate are individually configurable and are monitored online and in real time.

THE WELL

A three-chamber fluidic system ensures constant nutrition for cells. It is embedded with 3 sensors (pH, pO₂ and impedance) as well as a dedicated microscopy window to collect the maximum data per experiment.

Find more information about
our 24 well sensor plates.

Consumables

RESEARCH AREAS

Our ultimate multisensor cell analysis platform
can be involved in many research areas

Toxicology

Monitoring the multiple cellular reactions to toxic substances in defined treatment and washout protocols

Metabolic research

Observing cellular metabolic profiles in customised or standard protocols, such as the Metabolic Stress Test and the Glycolytic Stress Test

Oncology

Monitoring reactions of cancer cell lines and primary cancer cells to potential anticancer drugs

Drug screening

Parallel screening of potential drug candidates for their influence on different cell species in vitro

Basic cellular research

Observing how global key parameters of living cells react to external influences

Hypoxia research