Our technology allows researchers to measure changes in cell morphology and metabolism automatically and in a fully controllable atmospheric environment. It improves efficiency and work performance through the continuous observation of multiple data:
- dissolved oxygen
- cellular oxygen consumption rate (OCR)
- extracellular acidification rate (ECAR)
- cellular impedance (magnitude and phase) and microscopic imaging
AUTOMATION AND PREDICTABLE RESEARCH RESULTS, IN MUCH LESS TIME
CELL VIABILITY MEASURED IN
CYRIS® FLOX constantly monitors cell metabolism by measuring the OCR and the ECAR, and cell morphology by measuring cellular impedance and microscopic imaging.
Learn more about the performances of CYRIS® FLOX
INCYTOИ® platforms steadily observe cell viability automatically and in a fully controllable atmospheric environment
HOW IT WORKS
During the measurement, living adherent cells are cultivated and treated in the 24 independent test chambers of a special sensor-equipped microtiter plate (sensor plate), located in a temperature- and atmosphere- controlled climatic chamber.
A fully automated pipetting robot supplies and disposes of media and drugs in all 24 test chambers. This life support fluidic system allows the cells to be monitored and treated in the sensor plate for days up to several weeks in vital conditions and free of disturbance and contamination.
All measurements and treatment protocols in the sensor plate are individually configurable and are monitored online and in real time.
A three-chamber fluidic system ensures constant nutrition for cells. It is embedded with 3 sensors (pH, pO2 and impedance) as well as a dedicated microscopy window to collect the maximum data per experiment.
Find more information about
our 24 well sensor plates.
Our ultimate multisensor cell analysis platform
can be involved in many research areas
Monitoring the multiple cellular reactions to toxic substances in defined treatment and washout protocols
Observing cellular metabolic profiles in customised or standard protocols, such as the Metabolic Stress Test and the Glycolytic Stress Test
Monitoring reactions of cancer cell lines and primary cancer cells to potential anticancer drugs
Parallel screening of potential drug candidates for their influence on different cell species in vitro
Basic cellular research
Observing how global key parameters of living cells react to external influences
Monitoring of cellular reactions under controlled hypoxic atmospheric conditions